Abstract
Since 2011, the credibility of psychological science is in doubt. A major concern is that questionable research practices could have produced many false positive results, and it has been suggested that most published results are false. Here we present an empirical estimate of the false discovery risk using a z-curve analysis of randomly selected p-values from a broad range of journals that span most disciplines in psychology. The results suggest that no more than a quarter of published results could be false positives. We also show that the false positive risk can be reduced to less than 5% by using alpha = .01 as the criterion for statistical significance. This remedy can restore confidence in the direction of published effects. However, published effect sizes cannot be trusted because the z-curve analysis shows clear evidence of selection for significance that inflates effect size estimates.
Introduction
Several events in the early 2010s led to a credibility crisis in psychology. As journals selectively publish only statistically significant results, statistical significance loses its, well, significance. Every published focal hypothesis will be statistically significant, and it is unclear which of these results are true positives and which are false positives.
A key article that contributed to the credibility crisis was Simmons, Nelson, & Simonsohn’s article “False Positive Psychology: Undisclosed Flexibility in Data Collection and Analysis Allows Presenting Anything as Significant”
The title made a bold statement that it is easy to obtain statistically significant results even when the null-hypothesis is true. This led to concerns that many, if not most, published results are indeed false positive results. Many meta-psychological articles quoted Simmons et al.’s (2011) article to suggest that there is a high risk or even a high rate of false positive results in the psychological literature; including my own 2012 article.
“Researchers can use questionable research practices (e.g., snooping, not reporting failed studies, dropping dependent variables, etc.; Simmons et al., 2011; Strube, 2006) to dramatically increase the chances of obtaining a false-positive result” (Schimmack, 2012, p. 552, 248 citations)
The Appendix lists citations from influential meta-psychological articles that imply a high false positive risk in the psychological literature. Only one article suggested that fears about high false positive rates may be unwarranted (Strobe & Strack, 2014). In contrast, other articles have suggested that false positive rates might be as high as 50% or more (Szucs & Ioannidis, 2017).
There have been two noteworthy attempts at estimating the false discovery rate in psychology. Szucs and Ioannidis (2017) automatically extracted p-values from five psychology journals and estimated the average power of extracted t-tests. They then used this power estimate in combination with the assumption that psychologists discover one true, non-zero, effect for every 13 true null-hypotheses to suggest that the false discovery rate in psychology exceeds 50%. The problem with this estimate is that it relies on the questionable assumption that psychologists tests a very small percentage of true hypotheses.
The other article tried to estimate the false positive rate based on 70 of the 100 studies that were replicated in the Open Science Collaboration project (Open Science Collaboration, 2015). The statistical model estimated that psychologists test 93 true null-hypotheses for every 7 true effects (true positives), and that true effects are tested with 75% power (Johnson et al., 2017). This yields a false positive rate of about 50%. The main problem with this study is the reliance on a small, unrepresentative sample of studies that focused heavily on experimental social psychology, a field that triggered concerns about the credibility of psychology in general (Schimmack, 2020). Another problem is that point estimates based on a small sample are unreliable.
To provide new and better information about the false positive risk in psychology, we conducted a new investigation that addresses three limitations of the previous studies. First, we used hand-coding of focal hypothesis tests, rather than automatic extraction of all test-statistics. Second, we sampled from a broad range of journals that cover all areas of psychology rather than focusing narrowly on experimental psychology. Third, we used a validated method to estimate the false discovery risk based on an estimate of the expected discovery rate (Bartos & Schimmack, 2021). In short, the false discovery risk decreases as a monotonic function of the number of discoveries (i.e., p-values below .05) (Soric, 1989).
Z-curve relies on the observation that false positives and true positives produce different distributions of p-values. To fit a model to distributions of significant p-values, z-curve transforms p-values into absolute z-scores. We illustrate z-curve with two simulation studies. The first simulation is based on Simmons et al.’s (2011) scenario in which the combination of four questionable research practices inflates the false positive risk from 5% to 60%. In our simulation, we assumed an equal number of true null-hypotheses (effect size d = 0) and true hypotheses with small to moderate effect sizes (d = .2 to .5). The use of questionable research practices also increases the chances of getting a significant result for true hypotheses. In our simulation, the probability to get significance with true H0 was 58%, whereas the probability to get significance with true H1 was .93. Given the 1:1 ratio of H0 and H1 that were tested, this yields a false discovery rate of 39%.

Figure 1 shows that questionable research practices produce a steeply declining z-curve. Based on this shape, z-curve estimates a discovery rate of 5%, with a 95%CI ranging from 5% to 10%. This translates into estimates of the false discovery risk of 100% with a 95%CI ranging from 46% to 100% (Soric, 1989). The reason why z-curve provides a conservative estimate of the false discovery risk is that p-hacking changes the shape of the distribution in a way that produces even more z-values just above 1.96 than mere selection for significance would produce. In other words, p-hacking destroys evidential value when true hypotheses are being tested. It is not necessary to simulate scenarios in which even more true null-hypotheses are being tested because this would make the z-curve even steeper. Thus, Figure 1 provides a prediction for our z-curve analyses based on actual data, if psychologists heavily rely on Simmons et al.’s recipe to produce significant results.
Figure 2 is based on a simulation of Johnson et al.’s (2013) scenario with a 9% discovery rate (9 true hypotheses for very 100 hypothesis tests), a false discovery rate of 50%, and power to detect true effects of 75% (Figure 2). Johnson et al. did not assume or model p-hacking.

The z-curve for this scenario also shows a steep decline that can be attributed to the high percentage of false positive results. However, there is also a notable tail with z-values greater than 3 that reflects the influence of true hypotheses with adequate power. In this scenario, the expected discovery rate is higher with a 95%CI ranging from 7% to 20%. This translates into a 95%CI for the false discovery risk ranging from 21% to 71% (Soric, 1989). This interval contains the true value of 50%, although the point estimate, 34% underestimates the true value. Thus, we recommend to use the upper limit of the 95%CI as an estimate of the maximum false discovery rate that is consistent with data.
We now turn to real data. Figure 3 shows a z-curve analysis of Kühberger, Frity, and Scherndl (2014) data. The authors conducted an audit of psychological research by randomly sampling 1,000 English language articles published in the year 2007 that were listed in PsychInfo. This audit produced 344 significant p-values that could be subjected to a z-curve analysis. The results differ notably from the previous results. The expected discovery rate is higher and implies a much smaller false discovery risk of only 9%. However, due to the small set of studies, the confidence interval is wide and allows for nearly 50% false positive results.

To produce a larger set of test-statistics, my students and I have hand-coded over 1,000 randomly selected articles from a broad range of journals (Schimmack, 2021). These data were combined with Motyl et al.’s (2017) coding of social psychology journals. The time period spans the years 2008 to 2014, with a focus on the year 2010 and 2009. This dataset produced 1,715 significant p-values. The estimated false discovery risk is similar to the estimate for Kühberger et al.’s (2014) studies. Although the point estimate for the false discovery risk is a bit higher, 12%, the upper bound of the 95%CI is lower because the confidence interval is tighter.

Given the similarity of the results, we combined the two datasets to obtain an even more precise estimate of the false discovery risk based on 2,059 significant p-values. However, the upper limit of the 95%CI decreased only slightly from 30% to 26%.

The most important conclusion from these findings is that concerns about the amount of false positive results have exaggerated assumptions about the prevalence of false positive results in psychology journals. The present results suggest that at most a quarter of published results are false positives and that actual z-curves are very different from those implied by the influential simulation studies of Simmons et al. (2011). Our empirical results show no evidence that massive p-hacking is a common practice.
However, a false positive rate of 25% is still unacceptably high. Fortunately, there is an easy solution to this problem because the false discovery rate depends on the significance threshold. Based on their pessimistic estimates, Johnson et al. (2015) suggested to lower alpha to .005 or even .001. However, these stringent criteria would render most published results statistically non-significant. We suggest to lower alpha to .01. Figure 6 shows the rational for this recommendation by fitting z-curve with alpha = .01 (i.e., the red vertical line that represents the significance criterion is moved from 1.96 to 2.58.

Lowering alpha to .01, lowers the percentage of significant results from 83% (not counting marginally significant, p < .1, results) to 53%. Thus, the expected discovery decreases, but the more stringent criterion for significance lowers the false discovery risk to 4% and even the upper limit of the 95%CI is just 4%.
It is likely that discovery rates vary across journals and disciplines (Schimmack, 2021). In the future, it may be possible to make more specific recommendations for different disciplines or journals based on their discovery rates. Journals that publish riskier hypotheses tests or studies with modest power would need a more stringent significance criterion to maintain an acceptable false discovery risk.
An alpha level of .01 is also recommended by Simmons et al.’s (2011) simulation studies of p-hacking. Massive p-hacking that inflates the false positive risk from 5% to 61% produces only 22% false positives with alpha = .01. Milder forms of p-hacking inflates the false positive risk produces only a probability of 8% to obtain a p-value below .01. Ideally, open science practices like pre-registration will curb the use of questionable practices in the future. Increasing sample sizes will also help to lower the false positive risk. A z-curve analysis of new studies can be used to estimate the current false discovery risk and may suggest that even the traditional alpha level of .05 is able to maintain a false discovery risk below 5%.
While the present results may be considered good news relative to the scenario that most published results cannot be trusted, the results do not change the fact that some areas of psychology have a replication crisis (Open Science Collaboration, 2015). The z-curve results show clear evidence of selection for significance, which leads to inflated effect size estimates. Studies suggest that effect sizes are often inflated by more than 100% (Open Science Collaboration, 2015). Thus, published effect size estimates cannot be trusted even if p-values below .01 show the correct sign of an effect. The present results also imply that effect size meta-analyses that did not correct for publication bias produce inflated effect size estimates. For these reasons, many meta-analyses have to be reexamined and use statistical tools that correct for publication bias.
Appendix
“Given that these publishing biases are pervasive across scientific practice, it is possible that false positives heavily contaminate the neuroscience literature as well, and this problem may
affect at least as much, if not even more so, the most prominent journals” (Button et al., 2013; 3,316 citations).
“In a theoretical analysis, Ioannidis estimated that publishing and analytic practices make it likely that more than half of research results are false and therefore irreproducible” (Open Science Collaboration, 2015, aac4716-1)
“There is increasing concern that most current published research findings are false. (Ioannidis,
2005, abstract)” (Cumming, 2014, p7, 1,633 citations).
“In a recent article, Simmons, Nelson, and Simonsohn (2011) showed how, due to the misuse of statistical tools, significant results could easily turn out to be false positives (i.e., effects considered significant whereas the null hypothesis is actually true). (Leys et al., 2013, p. 765, 1,406 citations)
“During data analysis it can be difficult for researchers to recognize P-hacking or data dredging because confirmation and hindsight biases can encourage the acceptance of outcomes that fit expectations or desires as appropriate, and the rejection of outcomes that do not as the result of suboptimal designs or analyses. Hypotheses may emerge that fit the data and are then reported without indication or recognition of their post hoc origin. This, unfortunately, is not scientific discovery, but self-deception. Uncontrolled, it can dramatically increase the false discovery rate” (Munafò et al., 2017, p. 2, 1,010 citations)
Just how dramatic these effects can be was demonstrated by Simmons, Nelson, and Simonsohn (2011) in a series of experiments and simulations that showed how greatly QRPs increase the likelihood of finding support for a false hypothesis. (John et al., 2012, p. 524, 877 citations).
“Simonsohn’s simulations have shown that changes in a few data-analysis
decisions can increase the false-positive rate in a single study to 60%” (Nuzzo, 2014, 799 citations).
“the publication of an important article in Psychological Science showing how easily researchers can, in the absence of any real effects, nonetheless obtain statistically significant differences through various questionable research practices (QRPs) such as exploring multiple dependent variables or covariates and only reporting these when they yield significant results (Simmons, Nelson, & Simonsohn, 2011)” (Pashler & Wagenmakers, 2012, p. 528, 736 citations)
“Even seemingly conservative levels of p-hacking make it easy for researchers to find statistically significant support for nonexistent effects. Indeed, p-hacking can allow researchers to get most studies to reveal significant relationships between truly unrelated variables (Simmons et al., 2011).” (Simonsohn, Nelson, & Simmons, 2014, p. 534, 656 citations)
“Recent years have seen intense interest in the reproducibility of scientific results and the degree to which some problematic, but common, research practices may be responsible for high rates of false findings in the scientific literature, particularly within psychology but also more generally” (Poldrack et al., 2017, p. 115, 475 citations)
“especially in an environment in which multiple comparisons or researcher dfs (Simmons, Nelson, & Simonsohn, 2011) make it easy for researchers to find large and statistically significant effects that could arise from noise alone” (Gelman & Carlin,
“In an influential recent study, Simmons and colleagues demonstrated that even a moderate amount of flexibility in analysis choice—for example, selecting from among two DVs or
optionally including covariates in a regression analysis— could easily produce false-positive rates in excess of 60%, a figure they convincingly argue is probably a conservative
estimate (Simmons et al., 2011).” (Yarkoni & Westfall, 2017, p. 1103, 457 citations)
“In the face of human biases and the vested interest of the experimenter, such freedom of analysis provides access to a Pandora’s box of tricks that can be used to achieve any desired result (e.g., John et al., 2012; Simmons, Nelson, & Simonsohn, 2011″ (Wagenmakers et al., 2012, p. 633, 425 citations)
“Simmons et al. (2011) illustrated how easy it is to inflate Type I error rates when researchers employ hidden degrees of freedom in their analyses and design of studies (e.g., selecting the most desirable outcomes, letting the sample size depend on results of significance tests).” (Bakker et al., 2012, p. 545, 394 citations).
“Psychologists have recently become increasingly concerned about the likely overabundance of false positive results in the scientific literature. For example, Simmons, Nelson, and Simonsohn (2011) state that “In many cases, a researcher is more likely to falsely find
evidence that an effect exists than to correctly find evidence that it does not” (p. 1359)” (Maxwell, Lau, & Howard, 2015, p. 487,
“More-over, the highest impact journals famously tend to favor highly surprising results; this makes it easy to see how the proportion of false positive findings could be even higher in such journals.” (Pashler & Harris, 2012, p. 532, 373 citations)
“There is increasing concern that many published results are false positives [1,2] (but see [3]).” (Head et al., 2015, p. 1, 356 citations)
“Quantifying p-hacking is important because publication of false positives hinders scientific
progress” (Head et al., 2015, p. 2, 356 citations).
“To be sure, methodological discussions are important for any discipline, and both fraud and dubious research procedures are damaging to the image of any field and potentially undermine confidence in the validity of social psychological research findings. Thus far, however, no solid data exist on the prevalence of such research practices in either social or any other area of psychology.” (Strobe & Strack, 2014, p. 60, 291 citations)
“Assuming a realistic range of prior probabilities for null hypotheses, false report probability is likely to exceed 50% for the whole literature” (Szucs & Ioannidis, 2017, p. 1, 269 citations)
“Notably, if we consider the recent estimate of 13:1 H0:H1 odds [30], then FRP exceeds 50% even in the absence of bias” (Szucs & Ioannidis, 2017, p. 12, 269 citations)
“In all, the combination of low power, selective reporting, and other biases and errors that have been well documented suggest that high FRP can be expected in cognitive neuroscience and psychology. For example, if we consider the recent estimate of 13:1 H0:H1 odds [30], then
FRP exceeds 50% even in the absence of bias.” (Szucs & Ioannidis, 2017, p. 15, 269 citations)
“Many prominent researchers believe that as much as half of the scientific literature—not only in medicine, by also in psychology and other fields—may be wrong [11,13–15]” (Smaldino & McElreath, 2016, p. 2, 251 citations).
“Researchers can use questionable research practices (e.g., snooping, not reporting failed studies, dropping dependent variables, etc.; Simmons et al., 2011; Strube, 2006) to dramatically increase the chances of obtaining a false-positive result” (Schimmack, 2012, p. 552, 248 citations)
“A more recent article compellingly demonstrated how flexibility in data collection, analysis, and reporting can dramatically increase false-positive rates (Simmons, Nelson, & Simonsohn, 2011).” (Dick et al., 2015, p. 43, 208 citations)
“In 2011, we wrote “False-Positive Psychology” (Simmons et al. 2011), an article reporting the surprisingly severe consequences of selectively reporting data and analyses, a practice that we later called p-hacking. In that article, we showed that conducting multiple analyses on the same data set and then reporting only the one(s) that obtained statistical significance (e.g., analyzing multiple measures but reporting only one) can dramatically increase the likelihood of publishing a false-positive finding. Independently and nearly simultaneously, John et al. (2012) documented that a large fraction of psychological researchers admitted engaging in precisely the forms of p-hacking that we had considered. Identifying these realities—that researchers engage in p-hacking and that p-hacking makes it trivially easy to accumulate significant evidence for a false hypothesis—opened psychologists’ eyes to the fact that many published findings, and even whole literatures, could be false positive.” (Nelson, Simmons, & Simonsohn, 2018, 204 citations).
“As Simmons et al.(2011) concluded—reflecting broadly on the state of the discipline—“it is unacceptably easy to publish ‘statistically significant’ evidence consistent with any hypothesis”(p.1359)” (Earp & Trafimov, 2015, p. 4, 200 citations)
“The second, related set of events was the publication of articles by a series of authors (Ioannidis 2005, Kerr 1998, Simmons et al. 2011, Vul et al. 2009) criticizing questionable research practices (QRPs) that result in grossly inflated false positive error rates in the psychological literature” (Shrout & Rodgers, 2018, p. 489, 195 citations).
“Let us add a new dimension, which was brought up in a seminal publication of Simmons, Nelson & Simonsohn (2011). They stated that researchers actually have so much flexibility in deciding how to analyse their data that this flexibility allows them to coax statistically significant results from nearly any data set” (Forstmeier, Wagenmakers, & Parker, 2017, p. 1945, 173 citations)
“Publication bias (Ioannidis, 2005) and flexibility during data analyses (Simmons, Nelson, & Simonsohn, 2011) create a situation in which false positives are easy to publish, whereas contradictory null findings do not reach scientific journals (but see Nosek & Lakens, in press)” (Lakens & Evers, 2014, p. 278, 139 citations)
“Recent reports hold that allegedly common research practices allow psychologists to support just about any conclusion (Ioannidis, 2005; Simmons, Nelson, & Simonsohn, 2011).” (Koole & Lakens, 2012, p. 608, 139 citations)
“Researchers then may be tempted to write up and concoct papers around the significant results and send them to journals for publication. This outcome selection seems to be widespread practice in psychology [12], which implies a lot of false positive results in the literature and a massive overestimation of ES, especially in meta-analyses” (
“Researcher df, or researchers’ behavior directed at obtaining statistically significant results (Simonsohn, Nelson, & Simmons, 2013), which is also known as p-hacking or questionable research practices in the context of null hypothesis significance testing (e.g., O’Boyle, Banks, & Gonzalez-Mulé, 2014), results in a higher frequency of studies with false positives (Simmons et al., 2011) and inflates genuine effects (Bakker et al., 2012).” (van Assen, van Aert, & Wicherts, p. 294, 133 citations)
“The scientific community has witnessed growing concern about the high rate of false positives and unreliable results within the psychological literature, but the harmful impact
of false negatives has been largely ignored” (Vadillo, Konstantinidis, & Shanks, p. 87, 131 citations)
“Much of the debate has concerned habits (such as “phacking” and the filedrawer effect) which can boost the prevalence of false positives in the published literature (Ioannidis, Munafò, Fusar-Poli, Nosek, & David, 2014; Simmons, Nelson, & Simonsohn, 2011).” (Vadillo, Konstantinidis, & Shanks, p. 87, 131 citations)
“Simmons, Nelson, and Simonsohn (2011) showed that researchers without scruples can nearly always find a p < .05 in a data set if they set their minds to it.” (Crandall & Sherman, 2014, p. 96, 114 citations)